The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

The Mongolian Gerbil as a Model for the Analysis of Peripheral and Central Age-Dependent Hearing Loss

Age-dependent hearing loss involves pathological changes affecting the peripheral as well as the central auditory system. The Mongolian Gerbil is a rodent with an average life span of 3-4 years, which shows, in contrast to mice and rats, sensitive hearing in the frequency range that is important for human communication. Consequently, gerbils have been used to study structural and functional asp...

Age-related hearing loss: is it a preventable condition?

Numerous techniques have been tested to attempt to prevent the onset or progression of age-related hearing loss (ARHL): raising the animals in an augmented acoustic environment (used successfully in mouse and rat models), enhancing the antioxidant defenses with exogenous antioxidant treatments (used with mixed results in mouse and rat models), raising the animals with a calorie restricted diet ...

Development of the middle latency response in an animal model and its relation to the human response.

Although the clinical use of the middle latency response (MLR) in adults is fairly straightforward, its use is complicated by maturational changes that continue throughout the first decade of life. In order to telescope the time period of this long developmental course, we have approached the study of MLR maturation using the gerbil as an animal model. The course of MLR obtained over the tempor...

A statistical model for prediction of radiation induced sensorineural hearing loss in radiotherapy of brain

Introduction: The purpose of this study was to develop a statistical model for prediction of radiation induced sensorineural hearing loss (SNHL) induced by radiotherapy in patients with brain tumors.   Materials and Methods: CT scan of 18 patients (10 males and 8 females) with brain tumor who were referred to Radiation Center of Milad Hospital in Isfahan in 2...